Nov 14, 2025 · Trazodone, a commonly prescribed antidepressant also used for sleep, has been shown to cause false positive results on urine drug tests for amphetamines, MDMA, and LSD.

Jul 1, 2011 · Further, we found that patients taking trazodone can produce urine with sufficient m -CPP to result in false-positive Amphetamines II results. At our institution, false-positive amphetamine …

Dec 7, 2025 · A large clinical review found that medications like trazodone are among the most common sources of false positives in MDMA testing (Source: PubMed). If a false positive occurs, a lab will …

May 5, 2025 · Trazodone can cause false positives for LSD, PCP, and methadone on urine drug screens. Learn how to interpret results and what to do if you're taking trazodone.

Aug 14, 2025 · Trazodone can definitely cause false-positive results on urine drug screens, particularly for amphetamines and MDMA (ecstasy), due to its metabolite meta-chlorophenylpiperazine (m-CPP). …

Patients prescribed trazodone may encounter false-positive results in drug tests due to the presence of meta-chlorophenylpiperazine (m-CPP) in their urine. This substance can lead to false-positive …

Aug 10, 2022 · In fact, the drug you mention in your question, trazodone, has been linked to false-positive results. Trazodone has been linked to causing false-positives for several drugs, most …

Jun 6, 2025 · Certain medications can trigger a false positive on a urine drug test. Discover which medications can do this and how to respond to a false-positive result.

At our institution, false-positive amphetamine results occur not infrequently in patients taking trazodone with at least 8 trazodone-associated false-positive results during a single 26-day period. Laboratories …

Feb 28, 2025 · According to GoodRx, trazodone can lead to false positives for amphetamines or methamphetamines during urine drug tests. The presence of trazodone can stimulate the production …