Researchers have identified a previously unknown mechanism for maintaining cell function. Peroxisomes are essential cell organelles that play a vital role in lipid metabolism and cellular ...

Scientists at the University of Virginia School of Medicine have uncovered a key reason why some people continue to experience breathing problems long after recovering from COVID-19. Their research ...

Researchers at the University of Virginia (UVA) School of Medicine have uncovered a potential path to treatment for persistent COVID-19 symptoms impacting the lungs. The work, published in Science in ...

Peroxisome anatomy. Cross section of a cell organelle Peroxisome anatomy. Cross section of a cell organelle. Close-up of a Lipid bilayer Plasma membrane, Crystalline core, transport proteins. Vector ...

Saccharomyces cerevisiae Pex3p has been shown to act at the ER during de novo peroxisome formation. However, its steady state is at the peroxisomal membrane, where its role is debated. Here we show ...

This article was originally featured on Knowable Magazine. More than 1.5 billion years ago, a momentous thing happened: Two small, primitive cells became one. Perhaps more than any event—barring the ...

Impact of peroxisome dysfunction on cellular lipid metabolism and neuronal function Prof. Michael Schrader at the University of Exeter looks to understand the role of peroxisomes in human health and ...

Zellweger spectrum disorders (ZSDs) are a group of rare genetic diseases marked by a lack of functional peroxisomes caused by mutations in various PEX genes. Zellweger spectrum diseases are a subset ...

Senior and Reviewing Editor; The Barcelona Institute of Science and Technology, Spain In the interests of transparency, eLife publishes the most substantive revision requests and the accompanying ...

Peroxisomes are ubiquitous, oxidative subcellular organelles with important functions in cellular lipid metabolism and redox homeostasis. Loss of peroxisomal functions causes severe disorders with ...