San Francisco 49ers RB Christian McCaffrey bursts through the defense for a 41-yard run against the Chicago Bears.

McCaffrey’s cut left Jaylon Johnson grasping at air, and instead of bringing down San Francisco’s shifty running back, he ...

The case could be made that Christian McCaffrey is wearing down. The league leader in touches will need to conjure his ...

The Eagles have had one of the best defenses in football this season. Will it be able to slow down Brock Purdy and Christian ...

EAST RUTHERFORD, N.J. (AP) — Christian McCaffrey and Brian Robinson Jr. kept getting the ball and carving through the New York Giants’ defense. San Francisco 49ers coach Kyle Shanahan wondered if he ...

San Francisco 49ers running back Christian McCaffrey follows two perfect blocks en route to a 5-yard touchdown run.

Christian McCaffrey stiff-arms Giants cornerback Andru Phillips on his way to 173 total yards and two touchdowns in Sunday’s win at MetLife Stadium. EAST RUTHERFORD, N.J. — Christian McCaffrey and ...

SANTA CLARA, Calif. -- After another physical, grind-it-out win against the Los Angeles Rams last week, San Francisco 49ers running back Christian McCaffrey stood at a lectern with a big grin on his ...